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prepulse inhibition  (Schmid GmbH)

 
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    Schmid GmbH prepulse inhibition
    Prepulse Inhibition, supplied by Schmid GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/prepulse+inhibition/pre+pulse+inhibition++ppi++test/pmc10600934-48-32-34
    Average 90 stars, based on 1 article reviews
    prepulse inhibition - by Bioz Stars, 2026-09
    90/100 stars

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    Related Articles

    Inhibition:

    Article Title: Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans
    Article Snippet: .. Human studies of LSD have employed a variety of behavioural measures including facial emotion recognition, empathy, and social behaviour (Dolder, Schmid, Müller, Borgwardt, & Liechti, ); response inhibition (Schmidt et al., ); prepulse inhibition (Schmid et al . ); working memory and risk-based decision-making (Family et al., ; Pokorny et al., ); processing social influence (Duerler, Schilbach, Stämpfli, Vollenweider, & Preller, ); semantic processing (Family et al., ); attention, information processing, and cognitive control (Family et al., ; Hutten et al., ); time perception (Yanakieva et al., ); paired associates learning and memory, balance, and proprioception (Family et al., ). ..

    Control:

    Article Title: Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans
    Article Snippet: .. Human studies of LSD have employed a variety of behavioural measures including facial emotion recognition, empathy, and social behaviour (Dolder, Schmid, Müller, Borgwardt, & Liechti, ); response inhibition (Schmidt et al., ); prepulse inhibition (Schmid et al . ); working memory and risk-based decision-making (Family et al., ; Pokorny et al., ); processing social influence (Duerler, Schilbach, Stämpfli, Vollenweider, & Preller, ); semantic processing (Family et al., ); attention, information processing, and cognitive control (Family et al., ; Hutten et al., ); time perception (Yanakieva et al., ); paired associates learning and memory, balance, and proprioception (Family et al., ). ..



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    Fig. 3. Effects of HU-910 pretreatment on MK-801 and amphetamine-induced <t>PPI</t> disruption. (A) The disruptive effect of MK-801 treatment (0.25 mg/kg) in the PPI was attenuated by HU-910 (30 mg/kg) in all <t>prepulse</t> intensities. *p < 0.05 compared to vehicle+saline group (n = 9/group). (B) The startle response amplitude (pulse-only trials, arbitrary units, AU) was not modified by any treatment (C). Effect of HU-910 pretreatment on amphetamine-induced PPI disruption. The disruptive effect of amphetamine treatment (5 mg/kg) in the PPI was attenuated by HU-910 treatment at all doses tested on 80 dB prepulse intensity. On 85 dB and 90 dB prepulse intensities, HU-910 pretreatment attenuated PPI disruption only ate the dose of 3 mg/kg *p < 0.05 compared to vehicle+saline group (n = 10/group). (D) The startle response amplitude (pulse-only trials, arbitrary units, AU) was not modified by any treatment. Repeated-measures ANOVA followed by Turkey's test.
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    Image Search Results


    Timeline of the behavioral tests. Each animal completed all behavioral tests, except for Phenotyper that was performed only for a subset of animals: Phenotyper—myoclonus detection; CatWalk—walking pattern (coordination), speed of walk; Startle—startle response, prepulse inhibition; Beam walk—coordination; Elevated plus maze—hyperactivity, speed of walk; Grip strength—strength.

    Journal: Frontiers in Behavioral Neuroscience

    Article Title: In depth behavioral phenotyping unravels complex motor disturbances in Cstb −/− mouse, a model for progressive myoclonus epilepsy type 1

    doi: 10.3389/fnbeh.2023.1325051

    Figure Lengend Snippet: Timeline of the behavioral tests. Each animal completed all behavioral tests, except for Phenotyper that was performed only for a subset of animals: Phenotyper—myoclonus detection; CatWalk—walking pattern (coordination), speed of walk; Startle—startle response, prepulse inhibition; Beam walk—coordination; Elevated plus maze—hyperactivity, speed of walk; Grip strength—strength.

    Article Snippet: Startle response and prepulse inhibition (PPI) tests were performed using Startle Response (TSE Systems) operating on Startle Response/PPI Version 03.00 software.

    Techniques: Inhibition

    Cstb −/− mice show progressive myoclonus and altered startle response. (A) Myoclonic events were detected in PhenoTyper cages for a period of 3 h at 1.5, 3, and 6 months of age. (B) Progression of myoclonic events from 1.5 to 6 months of age in individual animals (see for separate graphs of Cstb −/− mice). (C) Cstb −/− mice show reduced startle response to 100 dB noise at 3, 5, and 6 months of age compared to the wild type ( wt ) mice. (D–F) Prepulse inhibition (PPI) at 69, 73, and 77 dB prepulse intensities is decreased in Cstb −/− mice at the age of 3 (D) , 5 (E) , and 6 (F) months. Data are presented as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001, N = 12 for (A,B) , N = 15–16 for (C–F) .

    Journal: Frontiers in Behavioral Neuroscience

    Article Title: In depth behavioral phenotyping unravels complex motor disturbances in Cstb −/− mouse, a model for progressive myoclonus epilepsy type 1

    doi: 10.3389/fnbeh.2023.1325051

    Figure Lengend Snippet: Cstb −/− mice show progressive myoclonus and altered startle response. (A) Myoclonic events were detected in PhenoTyper cages for a period of 3 h at 1.5, 3, and 6 months of age. (B) Progression of myoclonic events from 1.5 to 6 months of age in individual animals (see for separate graphs of Cstb −/− mice). (C) Cstb −/− mice show reduced startle response to 100 dB noise at 3, 5, and 6 months of age compared to the wild type ( wt ) mice. (D–F) Prepulse inhibition (PPI) at 69, 73, and 77 dB prepulse intensities is decreased in Cstb −/− mice at the age of 3 (D) , 5 (E) , and 6 (F) months. Data are presented as mean ± SD. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001, N = 12 for (A,B) , N = 15–16 for (C–F) .

    Article Snippet: Startle response and prepulse inhibition (PPI) tests were performed using Startle Response (TSE Systems) operating on Startle Response/PPI Version 03.00 software.

    Techniques: Inhibition

    Comparison of the symptoms in EPM1 patients and in Cstb −/− mice.

    Journal: Frontiers in Behavioral Neuroscience

    Article Title: In depth behavioral phenotyping unravels complex motor disturbances in Cstb −/− mouse, a model for progressive myoclonus epilepsy type 1

    doi: 10.3389/fnbeh.2023.1325051

    Figure Lengend Snippet: Comparison of the symptoms in EPM1 patients and in Cstb −/− mice.

    Article Snippet: Startle response and prepulse inhibition (PPI) tests were performed using Startle Response (TSE Systems) operating on Startle Response/PPI Version 03.00 software.

    Techniques: Comparison, Inhibition

    Fig. 3. Effects of HU-910 pretreatment on MK-801 and amphetamine-induced PPI disruption. (A) The disruptive effect of MK-801 treatment (0.25 mg/kg) in the PPI was attenuated by HU-910 (30 mg/kg) in all prepulse intensities. *p < 0.05 compared to vehicle+saline group (n = 9/group). (B) The startle response amplitude (pulse-only trials, arbitrary units, AU) was not modified by any treatment (C). Effect of HU-910 pretreatment on amphetamine-induced PPI disruption. The disruptive effect of amphetamine treatment (5 mg/kg) in the PPI was attenuated by HU-910 treatment at all doses tested on 80 dB prepulse intensity. On 85 dB and 90 dB prepulse intensities, HU-910 pretreatment attenuated PPI disruption only ate the dose of 3 mg/kg *p < 0.05 compared to vehicle+saline group (n = 10/group). (D) The startle response amplitude (pulse-only trials, arbitrary units, AU) was not modified by any treatment. Repeated-measures ANOVA followed by Turkey's test.

    Journal: Progress in neuro-psychopharmacology & biological psychiatry

    Article Title: HU-910, a CB2 receptor agonist, reverses behavioral changes in pharmacological rodent models for schizophrenia.

    doi: 10.1016/j.pnpbp.2022.110553

    Figure Lengend Snippet: Fig. 3. Effects of HU-910 pretreatment on MK-801 and amphetamine-induced PPI disruption. (A) The disruptive effect of MK-801 treatment (0.25 mg/kg) in the PPI was attenuated by HU-910 (30 mg/kg) in all prepulse intensities. *p < 0.05 compared to vehicle+saline group (n = 9/group). (B) The startle response amplitude (pulse-only trials, arbitrary units, AU) was not modified by any treatment (C). Effect of HU-910 pretreatment on amphetamine-induced PPI disruption. The disruptive effect of amphetamine treatment (5 mg/kg) in the PPI was attenuated by HU-910 treatment at all doses tested on 80 dB prepulse intensity. On 85 dB and 90 dB prepulse intensities, HU-910 pretreatment attenuated PPI disruption only ate the dose of 3 mg/kg *p < 0.05 compared to vehicle+saline group (n = 10/group). (D) The startle response amplitude (pulse-only trials, arbitrary units, AU) was not modified by any treatment. Repeated-measures ANOVA followed by Turkey's test.

    Article Snippet: The prepulse inhibition (PPI) test was performed simultaneously on two identical startle response systems (Med Associates, USA) with a constant 65 dB background noise.

    Techniques: Disruption, Saline, Modification